其它名称：免疫球蛋白IgG4抗体，抗人IgG4抗体，IgG4 Antibody

货号：G801015

种类：抗体

应用：LETIA

特异性：Human IgG4

来源：Mouse

存贮：-20℃

产品说明

IgG4 is a subclass of immunoglobulin G. Its role in the inflammation is still being defined, as the significance of its anti-inflammatory activity and tolerance-inducing properties is counteracted by its pathogenic features present in recently identified IgG4-dependent diseases. IgG4 is the least numerous of four IgG subclasses and accounts for only about 5% of IgG immunoglobulins in the human body. Its unique properties, dissimilar to other IgGs, are the lack of influence on the classical complement component pathway and, through a property called “fab-arm exchange” (FAE), inhibition of the formation of large immune complexes